pFind Studio: a computational solution for mass spectrometry-based proteomics


2018 -  2017 -  2016 -  2015 -  2014 -  2013 - 2012 - 2011 - 2010 -  2009 -  2008 -  2007 or earlier


Molecular & cellular Proteomics. Jan 8, 2019.[abstract]
Precision de novo peptide sequencing using mirror proteases of Ac-LysargiNase and trypsin for large-scale proteomics
Hao Yang, Yanchang Li, Mingzhi Zhao, Feilin Wu, Xi Wang, Weidi Xiao, Yihao wang, Junling Zhang, Fuqiang Wang, Feng Xu, Wen-Feng Zeng, Christopher M. Overall, Si-Min He, Hao Chi and Ping Xu.


Nature Biotechnology. October 8, 2018.[abstract]
Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine.
Hao Chi, Chao Liu, Hao Yang, Wen-Feng Zeng, Long Wu, Wen-Jing Zhou, Rui-Min Wang, Xiu-Nan Niu, Yue-He Ding, Yao Zhang, Zhao-Wei Wang, Zhen-Lin Chen, Rui-Xiang Sun, Tao Liu, Guang-Ming Tan, Meng-Qiu Dong, Ping Xu, Pei-Heng Zhang & Si-Min He.
SCI Citation: 1 (Last updated: Feb 26, 2019)


Journal of proteome research. November 13, 2017.[abstract]
pSite: Amino Acid Confidence Evaluation for Quality Control of De Novo Peptide Sequencing and Modification Site Localization.
Hao Yang, Hao Chi, Wen-Jing Zhou, Wen-Feng Zeng, Chao Liu, Rui-Min Wang, Zhao-Wei Wang, Xiu-Nan Niu, Zhen-Lin Chen, and Si-Min He.
SCI Citation: 2 (Last updated: Feb 26, 2019)

Analytical Chemistry. November 10, 2017.[abstract]
pDeep: Predicting MS/MS Spectra of Peptides with Deep Learning.
Xie-Xuan Zhou, Wen-Feng Zeng, Hao Chi, Chun-Jie Luo, Chao Liu, Jian-Feng Zhan, Si-Min He, and Zhi-Fei Zhang.
SCI Citation: 6 (Last updated: Feb 26, 2019)

Nature Communications. September 5, 2017.[abstract]
pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification.
Ming-Qi Liu, Wen-Feng Zeng, Pan Fang, Wei-Qian Cao, Chao Liu, Guo-Quan Yan, Yang Zhang, Chao Peng, Jian-Qiang Wu, Xiao-Jin Zhang, Hui-Jun Tu, Hao Chi, Rui-Xiang Sun, Yong Cao, Meng-Qiu Dong, Bi-Yun Jiang, Jiang-Ming Huang, Hua-Li Shen, Catherine C. L. Wong, Si-Min He, Peng-Yuan Yang.
SCI Citation: 20 (Last updated: Feb 26, 2019)


Journal of proteome research. December 26, 2016.[abstract]
Open-pNovo: De Novo Peptide Sequencing with Thousands of Protein Modifications.
Hao Yang, Hao Chi, Wen-Jing Zhou, Wen-Feng Zeng, Kun He, Chao Liu, Rui-Xiang Sun, Si-Min He.
SCI Citation: 7 (Last updated: Feb 26, 2019)

Scientific Reports. May 3, 2016.[abstract]
pGlyco: a pipeline for the identification of intact N-glycopeptides by using HCD- and CID-MS/MS and MS3.
Wen-Feng Zeng, Ming-Qi Liu, Yang Zhang, Jian-Qiang Wu, Pan Fang, Chao Peng, Aiying Nie, Guoquan Yan, Weiqian Cao, Chao Liu, Hao Chi, Rui-Xiang Sun, Catherine C. L. Wong, Si-Min He, Pengyuan Yang.
SCI Citation: 28 (Last updated: Feb 26, 2019)

生物化学与生物物理进展. April 21, 2016.[abstract]
SCI Citation: 3 (Last updated: March 8, 2018)

Analytical Chemistry. February 4, 2016.[abstract]
pTop 1.0: a High-accuracy and High-efficiency Search Engine for Intact Protein Identification.
Rui-Xiang Sun, Lan Luo, Long Wu, Rui-Min Wang, Wen-Feng Zeng, Hao Chi, Chao Liu, Si-Min He.
SCI Citation: 18 (Last updated: Feb 26, 2019)


Journal of Proteomics. July 1, 2015.[abstract]
pFind-Alioth: A novel unrestricted database search algorithm to improve the interpretation of high-resolution MS/MS data.
Hao Chi, Kun He, Bing Yang, Zhen Chen, Rui-Xiang Sun, Sheng-Bo Fan, Kun Zhang, Chao Liu, Zuo-Fei Yuan, Quan-Hui Wang, Si-Qi Liu, Meng-Qiu Dong, Si-Min He.
SCI Citation: 16 (Last updated: Feb 26, 2019)

Bioinformatics. May 27, 2015. [abstract]
A Note on the False Discovery Rate of Novel Peptides in Proteogenomics.
Kun Zhang, Yan Fu, Wen-Feng Zeng, Kun He, Hao Chi, Chao Liu, Yan-Chang Li, Yuan Gao, Ping Xu, Si-Min He.
SCI Citation: 14 (Last updated: Feb 26, 2019)

Current Protocols in Bioinformatics. March 2015. [abstract]
Using pLink to Analyze Cross-Linked Peptides.
Sheng-Bo Fan, Jia-Ming Meng, Shan Lu, Kun Zhang, Hao Yang, Hao Chi, Rui-Xiang Sun, Meng-Qiu Dong, Si-Min He.

Nature Methods. Feb. 9, 2015. [abstract]
Mapping native disulfide bonds at a proteome scale.
Shan Lu, Sheng-Bo Fan, Bing Yang, Yu-Xin Li, Jia-Ming Meng, Long Wu, Pin Li, Kun Zhang, Mei-Jun Zhang, Yan Fu, Jin-Cai Luo, Rui-Xiang Sun, Si-Min He, Meng-Qiu Dong.
SCI Citation: 40 (Last updated: Feb 26, 2019)

生物化学与生物物理进展. 2015, 42(2):101-104. [abstract]


生物化学与生物物理进展. May 26, 2014. 41(11):1109-1125. [abstract]
SCI Citation: 2 (Last updated: Feb 26, 2019)

Anal Chem. May 3, 2014. 86(11):5286-94. [abstract]
pQuant Improves Quantitation by Keeping out Interfering Signals and Evaluating the Accuracy of Calculated Ratios.
Chao Liu, Chun-Qing Song, Zuo-Fei Yuan, Yan Fu, Hao Chi, Le-Heng Wang, Sheng-Bo Fan, Kun Zhang, Wen-Feng Zeng, Si-Min He, Meng-Qiu Dong, and Rui-Xiang Sun.
SCI Citation: 22 (Last updated: Feb 26, 2019)


生物化学与生物物理进展. Jan 28, 2013. [abstract]
SCI Citation: 2 (Last updated: August 29, 2017)

Journal of Proteome Research. Feb. 1, 2013. [abstract]
pNovo+: De Novo Peptide Sequencing Using Complementary HCD and ETD Tandem Mass Spectra.
Hao Chi, Hai-Feng Chen, Kun He, Long Wu, Bing Yang, Rui-Xiang Sun, Jian-Yun Liu, Wen-Feng Zeng, Chun-Qing Song, Si-Min He, Meng-Qiu Dong.
SCI Citation: 44 (Last updated: Feb 26, 2019)


生物化学与生物物理进展. Aug 10, 2012. [abstract]
SCI Citation: 2(Last updated: March 8, 2018)

Nature Methods. July 08, 2012. [abstract]
Identification of cross-linked peptides from complex samples.
Bing Yang, Yan-Jie Wu, Ming Zhu, Sheng-Bo Fan, Jin-Zhong Lin, Kun Zhang, Shuang Li, Hao Chi, Yu-Xin Li, Hai-Feng Chen, Shu-Kun Luo, Yue-He Ding, Le-Heng Wang, Zhi-Qi Hao, Li-Yun Xiu, She Chen, Ke-Qiong Ye, Si-Min He and Meng-Qiu Dong.
SCI Citation: 210 (Last updated: Feb 26, 2019)

Proceedings of the National Academy of Sciences. January 31, 2012. [abstract]
Nematode sperm maturation triggered by protease involves sperm-secreted serine protease inhibitor (Serpin).
Yanmei Zhao, Wei Sun, Pan Zhang, Hao Chi, Mei-Jun Zhang, Chun-Qing Song, Xuan Ma, Yunlong Shang, Bin Wang, Youqiao Hu, Zhiqi Hao, Andreas F.Huhmei, Fanxia Meng, Steven W.L'Hernault, Si-Min He, Meng-Qiu Dong and Long Miao.
SCI Citation: 29 (Last updated: Dec 14, 2018)

Proteomics, Volume 12, Issue 2, pages 226–235, No. 2 January 2012. [abstract]
pParse: a method for accurate determination of monoisotopic peaks in high-resolution mass spectra.
Zuo-Fei Yuan, Chao Liu, Hai-Peng Wang, Rui-Xiang Sun, Yan Fu, Jing-Fen Zhang, Le-Heng Wang, Hao Chi, You Li, Li-Yun Xiu, Wen-Ping Wang, Si-Min He.
SCI Citation: 26 (Last updated: Feb 26, 2019)


Molecular & Cellular Proteomics. 2011, 10(5). [abstract]
DeltAMT: A Statistical Algorithm for Fast Detection of Protein Modifications From LC-MS/MS Data.
Yan Fu, Li-Yun Xiu, Wei Jia, Ding Ye, Rui-Xiang Sun, Xiao-Hong Qian, and Si-Min He.
SCI Citation: 17 (Last updated: Feb 26, 2019)


色谱. 2010, 28(6):529-534. [abstract]
SCI Citation: 3 (Last updated: August 29, 2017)

BMC Bioinformatics. 2010, 11:577. [abstract]
Speeding up tandem mass spectrometry-based database searching by longest common prefix.
Chen Zhou, Hao Chi, Le-Heng Wang, You Li, Yan-Jie Wu, Yan Fu, Rui-Xiang Sun, Si-Min He.
SCI Citation: 3 (Last updated: August 29, 2017)

Journal of Proteome Research. 2010, 9(12):6354–6367. [abstract]
Improved Peptide Identification for Proteomic Analysis Based on Comprehensive Characterization of Electron Transfer Dissociation Spectra.
Rui-Xiang Sun, Meng-Qiu Dong, Chun-Qing Song, Hao Chi, Bing Yang, Li-Yun Xiu, Li Tao, Zhi-Yi Jing, Chao Liu, Le-Heng Wang, Yan Fu, and Si-Min He.
SCI Citation: 34 (Last updated: Nov 11, 2018)

生物化学与生物物理进展. 2010, (1). [abstract]
SCI Citation: 10 (Last updated: August 29, 2017)

Rapid Communications in Mass Spectrometry. 2010, 24(12):1791-1798. [abstract]
An efficient parallelization of phosphorylated peptide and protein identification.
Leheng Wang, Wenping Wang, Hao Chi, Yanjie Wu, You Li, Yan Fu, Chen Zhou, Ruixiang Sun, Haipeng Wang, Chao Liu, Zuofei Yuan, Liyun Xiu, Si-Min He.
SCI Citation: 6 (Last updated: August 29, 2017)

Proceedings of the 18th Annual International Conference on Intelligent System for Molecular Biology (ISMB 2010), also appears in Bioinformatics. 2010, 26(12):i399-i406. [abstract]
Open MS/MS Spectral Library Search to Identify Unanticipated Post-Translational Modifications and Increase Spectral Identification Rate.
Ding Ye, Yan Fu, Rui-Xiang Sun, Hai-Peng Wang, Zuo-Fei Yuan, Hao Chi and Si-Min He.
SCI Citation: 47 (Last updated: Feb 26, 2019)

Journal of Proteome Research, 9 (5), 2713–2724, 2010. [abstract]
pNovo: De novo Peptide Sequencing and Identification Using HCD Spectra.
Hao Chi , Rui-Xiang Sun , Bing Yang , Chun-Qing Song , Leheng Wang , Chao Liu , Yan Fu , Zuo-Fei Yuan , Hai-Peng Wang , Si-Min He and Meng-Qiu Dong.
SCI Citation: 96 (Last updated: Feb 26, 2019)

Rapid Communications in Mass Spectrometry, 24:807 - 814, 2010. [abstract]
Speeding up tandem mass spectrometry based database searching by peptide and spectrum indexing.
You Li, Hao Chi, Le-Heng Wang, Hai-Peng Wang, Yan Fu, Zuo-Fei Yuan, Su-Jun Li, Yan-Sheng Liu, Rui-Xiang Sun, Rong Zeng, Si-Min He.
SCI Citation: 23 (Last updated: March 8, 2018)


Rapid Commun. Mass Spectrom. 2009; 23: 3448–3456. [abstract]
Isotope pattern vector based tandem mass spectral data calibration for improved peptide and protein identification.
Jingfen Zhang, Dong Xu, Wen Gao, Guohui Lin and Simin He.
SCI Citation: 2 (Last updated: August 29, 2017)

Molecular & Cellular Proteomics, 8:913-923, 2009. [abstract]
A Strategy for Precise and Large-Scale Identification of Core Fucosylated Glycoproteins.
Wei Jia, Zhuang Lu, Yan Fu, Hai-Peng Wang, Le-Heng Wang, Hao Chi, Zuo-Fei Yuan, Zhao-Bin Zheng, Li-Na Song, Huan-Huan Han, Yi-Min Liang, Jing-Lan Wang, Yun Cai, Yu-Kui Zhang, Yu-Lin Deng, Wan-Tao Ying, Si-Min He, and Xiao-Hong Qian.
SCI Citation: 59 (Last updated: Feb 26, 2019)

Accepted by APBC 2009, BMC Bioinformatics, 10(Suppl 1): S50, 2009. [abstract]
Efficient discovery of abundant post-translational modifications and spectral pairs using peptide mass and retention time differences.
Yan Fu, Wei Jia, Zhuang Lu, Haipeng Wang, Zuofei Yuan, Hao Chi, You Li, Liyun Xiu, Wenping Wang, Chao Liu, Leheng Wang, Ruixiang Sun, Wen Gao, Xiaohong Qian, Si-Min He.
SCI Citation: 8 (Last updated: August 29, 2017)


Rapid Communications in Mass Spectrometry,22,1203-1212,2008. [abstract]
PeakSelect:preprocessing tandem mass spectra for better peptide identification.
Jing-Fen Zhang, Si-Min He, Charles X.Ling, Xing-Jun Cao, Rong Zeng and Wen Gao.
SCI Citation: 16 (Last updated: Feb 26, 2019)


Rapid Communications in Mass Spectrometry, 21,2985-2991,2007. [abstract]
pFind 2.0: a software package for peptide and protein identification via tandem mass spectrometry.
Le-Heng Wang, De-Quan Li, Yan Fu, Hai-Peng Wang, Jing-Fen Zhang, Zuo-Fei Yuan,Rui-Xiang Sun, Rong Zeng, Si-Min He, Wen Gao.
SCI Citation: 117 (Last updated: Feb 26, 2019)

Proceedings of the 12th Pacific Symposium on Biocomputing, 421-432, 2007. [abstract]
Mining tandem mass spectral data for more accurate mass error model for peptide identification.
Yan Fu, Wen Gao, Si-Min He, Rui-Xiang Sun, Hu Zhou, Rong Zeng.

中国科学 E辑 信息科学 36(2): 222-234, 2006. [abstract]
SCI Citation: 3 (Last updated: August 29, 2017)

Proceedings of the Pacific Symposium on Biocomputing, 303-314, 2006. [abstract]
An SVM Scorer for More Sensitive and Reliable Peptide Identification via Tandem Mass Spectrometry.
Hai-Peng Wang, Yan Fu, Rui-Xiang Sun, Si-Min He, Rong Zeng, Wen Gao.
SCI Citation: 5 (Last updated: May 7, 2017)

Bioinformatics, 22(20), 2572-2573, 2006. [abstract]
IndexToolkit: An Open Source Toolbox to Index Protein Databases for High-throughput Proteomics.
De-Quan Li, Wen Gao, Charles X. Ling, Xiaobiao Wang, Rui-Xiang Sun, and Si-Min He.
SCI Citation: 4 (Last updated: August 29, 2017)

IEEE/ACM Transactions on Computational Biology and Bioinformatics,2(3), 217-230, 2005. [abstract]
Predicting Molecular Formulas of Fragment Ions with Isotope Patterns in Tandem Mass Spectra.
Jing-Fen Zhang, Wen Gao, Jingjing Cai, Si-Min He, Rong Zeng, and Run-Sheng Chen.
SCI Citation: 21 (Last updated: Dec 14, 2018)

Genomics, Proteomics & Bioinformatics, 3(4), 231-237, 2005. [abstract]
Preprocessing of tandem mass spectrometric data based on decision tree classification.
Jing-Fen Zhang, Si-Min He, Jingjing Cai, Xing-Jun Cao, Rui-Xiang Sun, Yan Fu, Rong Zeng and Wen Gao.
SCI Citation: 5 (Last updated: August 29, 2017)

Bioinformatics, 21(13), 3049-3050, 2005. [abstract]
pFind: a novel database-searching software system for automated peptide and protein identification via tandem mass spectrometry.
De-Quan Li, Yan Fu, Rui-Xiang Sun, Charles X. Ling, Yonggang Wei, Hu Zhou, Rong Zeng, Qiang Yang, Si-Min He and Wen Gao.
SCI Citation: 84 (Last updated: Feb 26, 2019)

Bioinformatics 20, 1948-1954, 2004. [abstract]
Exploiting the kernel trick to correlate fragment ions for peptide identification via tandem mass spectrometry.
Yan Fu, Qiang Yang, Rui-Xiang Sun, De-Quan Li, Rong Zeng, Charles X. Ling, Wen Gao.
SCI Citation: 80 (Last updated: Feb 26, 2019)

In Proceedings of the 8th Pacific Rim International Conference on Artificial Intelligence (PRICAI 2004), Auckland, New Zealand, August 9-13, 2004, LNAI 3157, 544–553. [abstract]
A Kernel-based Case Retrieval Algorithm with Application to Bioinformatics.
Yan Fu, Qiang Yang, Charles X. Ling, Hai-Peng Wang, De-Quan Li, Rui-Xiang Sun, Hu Zhou, Rong Zeng, Yiqiang Chen, Si-Min He, Wen Gao.