pFind Studio: a computational solution for mass spectrometry-based proteomics


pTop is a software dedicated for the analysis of intact protein using mass spectrometry. It can support the complex data sets with ultra-modifications.

The main flow is shown below.

Cite us

1. pTop 1.0: a High-accuracy and High-efficiency Search Engine for Intact Protein Identification.
Rui-Xiang Sun, Lan Luo, Long Wu, Rui-Min Wang, Wen-Feng Zeng, Hao Chi, Chao Liu, and Si-Min He.

Anal Chem 88, 3082-3090 (2016). [abstract]

Notice: please quote these above publications when you use pTop software in your papers.


You can download this file user_guide.pdf, which tells you how to use pTop.

Please read carefully the pTop Software License Agreement.

pTop v1.2 is currently free to use. Download pTop v1.2. You can use example dataset to test pTop. Download example dataset.


* After installation, you need to activate the software. Just fill in some registration information when you first launch pTop 1.0 and send them to to get the license file.

* If pTop expired, please redownload the software and reinstall it. Thanks for your support!

* If you have any problem, please email to: ptop[at]

Version history

Release version Release date Click for more
pTop v1.2 2016-06-20 Download Release Notes